hyperparathyroidism

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hyperparathyroidism

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10 Posts

me007
Forum Guru

Topics: 72
Posts: 803

01/13/07 - 11:48 AM

Why there is a diastolic hypertension in hyperparathyroidism?

ellen
Forum Senior

Topics: 17
Posts: 128

01/13/07 - 03:17 PM

primary hyperparathyroidism...diastolic hypertension....bcz...hypercalcemia.

me007
Forum Guru

Topics: 72
Posts: 803

01/13/07 - 05:18 PM

missing something...
Why calcium cause vasoconstriction?

babydoc4usmle
Forum Guru
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Topics: 18
Posts: 634

01/13/07 - 06:45 PM

hypercalcemia provides extra Ca available for myocardial contracion --> increase in force of contraction with incr peak LVP
same with vessels: incr Ca-->incr tone

Ancylostoma
Forum Guru

Topics: 42
Posts: 642

01/13/07 - 09:41 PM

I would agree, the smooth muscle and cardiac muscle use extracellular calcium to augment there action via calcium channel. These calcium channels are the same ones that verapamil blocks and thus verapamil has an effect on both the heart and the Blood vessels. Verapamil doesnt work on skeletal muscle because of the lact of these channels.

MRMAVERICK
Forum Guru
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Topics: 42
Posts: 749

01/14/07 - 09:16 AM

babydoc if incresed contarctility was cause it wud lead t0 systolic htn
its increase in tpr which leads to diastolic htn

the star
Forum Newbie

Topics: 0
Posts: 2

01/26/07 - 06:23 AM

parameter wrote:

babydoc if incresed contarctility was cause it wud lead t0 systolic htn
its increase in tpr which leads to diastolic htn

can you clearify it more ???

Luckyall
Forum Guru

Topics: 11
Posts: 593

01/26/07 - 08:13 AM

DBP --> is the amount of blood in the Ao after Ventric sistoli
If the blood runs fast from Ao to perif vasculature----> decr DBP
If blood stays in Ao----> incr DBP
In Hyper PTH- ism-----> there is Metaboloc ACIDOSIS----> DEcrease Myocard Contractility---> Decrease Myocard Contractility---> DHTN

babydoc4usmle
Forum Guru
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Topics: 18
Posts: 634

01/26/07 - 08:40 AM

the point was, that DBP defined not by contractility of ventricles, but by the resistance of the arterioles: more resistance - more pressure should be applyed to push blood through
so by increasing Ca you incr vascular tone and DBP goes up

Luckyall
Forum Guru

Topics: 11
Posts: 593

01/26/07 - 09:41 AM

#10

less blood in vessels ( low DBP) could be either
1) vasodilation.
2)blood runs faster ( Hyperthyroidism, or AV fistula)
3) or Ventric pump dont function properly... less blood is pumped out
So the DBP it CAN be related to V pump !!!!!!!

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