Clozapine
Forum Elite
Topics: 15
Posts: 167
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I`m taking my exam on Feb 17th (hopefully!! have no intention to postpone it further).
Doing pharma right now. Have the rest of the night to go thru last 3 sections (6 chapters).
Good luck to all !! hang in there and lets get done with it 
S
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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1) Patients with pheochromocytoma in OR ~ which inhaled anesthetic cannot be used? Halothene ~ sensetizes heart to catecholamines
2) Inhaled anesthetic causing megaloblastic anaemia in chronic exposure ( staff working in poorly ventilated dental OR) ~ Nitrous Oxide
3) Inhaled anesthetic with low blood gas partition coeff, but patients hold their breath due to pungent smell ~ not used for induction of anaesthesia ~ Desflurane
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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anti-seizure drug causing peripheral neuropathy ~ requires F/U examination for deep tendon reflex activity in lower extremities (in chronic use)
~ Phenytoin
Epileptic patient on treatment enrolls for methadone maintainance program, withdrawal effects more pronounced ~ due to enzyme inducing effects of phenytoin/carbamazepine --> increased metabolism of methadone
Although Ethosuxamide has a t1/2 of 40 hours the dosage is twice daily to reduce the severity of GI distress
Withdrawal is least likely to be a problem with which anti-seizure drug?
~ Ethosuxamide (absence seizure Tx withdrawal is easier than withdrawal from drugs used for tonic-clonic or partial seizures)
Carbamazepine not used in absence or myocloinic seizures ~ reported to worsen them
Effective blood level for Ethosuxamide and Valproic acid is 50-100 mg/L ; seizure recurrence if plasma level drops below 50 mg/L in chronic Tx (caution: theraputic window narrow, so plasma level monitoring required)
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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I`m in love with the espresso machine ... can I take it to the prometric ? any ideas anyone ? Will do alcohol and sedative/hypnotic now ... these chapters are makin me drowsy ...zzzz
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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MORE FUN STUFF 
Q. 1. Why does ethanol show zero-order kinetics???
Q. 2. What are the NTMs ethanol appear to facilitate/inhibit???
Q. 3. What other enzyme (other than Alcohol DH) contributes to ethanol metabolism and @ what blood level of ethanol???
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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Ans.1. Due to limited supply of NAD+ required in ethanol metabolism ---> fixed
capacity of ethanol metabolism = 7-10 gm/h
Ans.2. Facilitates action of GABA @ GABA(A) receptor
Inhibits binding of Glutamate to NMDA receptor
Ans.3. MEOS (Microsomal Ethanol Oxidizing System) @ >100 mg/dL of blood level
of Ethanol
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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Drugs acting on the craziest ion channel :P GABA(A) Receptor
Activators:
-BZ
-Barbis
-Zolpidem, Zaleplon
-Alcohol
-Alphaxolone(a steroid aneasthetic)
-Etomidate
-Propofol
-Halothene
-Anticonvulsants (Gabapentin, Vigabartin)
-Ivermectin !!!
Blockers:
-Picrotoxin (dirct channel blocker)
-Bicucullin (inhibits GABA binding to receptor)
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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Was planning to nail pharma, which I`ve been trying to for past few days .... couldn`t make it  ... ... too freaking bad ... will allow myself one more day (today/13th) only, plus mycology and parasitology from micro .... and some virology if possible .....
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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Okay... today's agenda
Blood
Endocrine
Inflammatory
Anticancer
Immunopharma
Toxicology
Antifungal
Antiparasitic
Antiviral
Total time: 12 hours from now,
Will keep on posting more fun stuff
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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Hmmm.... it's time I officially quit obsessing over pharma .... moving on to immuno tonight ...
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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I was supposed to start B/S today ... but still stuck with Immuno .... will finish immunology and immunopatho from goljan tonight ... and possibly the rest of the pharm
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| kamyabi
Forum Junior
Topics: 1
Posts: 113
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You are doing a great job !!! Wish you all the best .
I read your advice on Anatomy forum. Do you recommend HY for Histo also ?
___________________
Success does not come to those who wish for it, but to those who work for it.
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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Thanks so much Kamyabi I hope God gives me the strength to go thru this time.
To be honest, I`m in no place to recommend, you know!! I`d suggest you to follow the path of 99'ers .... but if you ask MY opinion, I`d say I found HY histology more informative than Kaplan, at least go thru the chapters for epithelial tissue/cell junctions, Connective tissue, bone, cartilage and whatever you think is missing in Kaplan. It kinda combines pathology so I thought it was more helpful for correlation.
But if you are doing goljan big book, you might find it redundant
All the very best for your prep and your exam.
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| kamyabi
Forum Junior
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Posts: 113
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Thank you very much for your kind reply and good wishes. Will definitely go for HY histology now.
Wish you a wonderful prep and a 99 
___________________
Success does not come to those who wish for it, but to those who work for it.
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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Thank you kamyabi ... this forum keeps me going against all odds.
I`m starting B/S today. Hope to finish it by tonight....
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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I`m starting to lose tempo .... and I`m having hard time with Physician/patient relationship .... sometimes the answers don`t make any sense to me .... anyways, will start doing micro today. Today and tomorrow is for micro ....
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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I guess I`ll need one more day for micro... I have three classes this week .. and two assignments ... hate it ....
Anyways, will do general and systemic bacteriology today with antibiotics (from pharm) and bacterial genetics
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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`Morning everyone. I have to HAVE TO finish micro today 
I never finished a few chapters from pharm and B/S, but have to squeeze them in somewhere in my schedule  .... anyways, whatever it takes, will nail micro by tonight
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| mytime
Kick my butt!
Topics: 39
Posts: 3,174
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HEY CLOZ. u are doing great.....Keep up the good work. What about qs...? Hope u are doing lots and scoring great! GL, pal!
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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Hey mytime Thanks for swinging by ... I love your avatar
Well, I haven`t started doing questions yet .... except for the end of the chapter questions from kaplan+/- Lange book series. For some of the subjects, this is my first read... like immuno, B/S and part of pharm and most of the patho ... which is pretty crazy ... but I need to juggle my work, school and USMLE prep and I need to be done with it before my midterms
Planning to finish all the subjects by Jan 30th and then a marathon UW (7 blocks a day) ( 7 hour for solving+ 7-10 hours explanations) ....
will definitely update how I`m surviving this :P
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| mytime
Kick my butt!
Topics: 39
Posts: 3,174
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CLOZ love my avtar too!   Listen up u better do more qs. before u get to UW..alright? Just so u get a better score with UW. otherwise all esle seems ok. saw u paid my thread a visit, ehh? Liked it? That's so sweet! Keep in touch! study hard and study smart!
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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Thanks mytime .... I know I shud be doing questions, but to me, it doesn`t make sense to solve q`s before knowing the stuff thoroughly .... I know i`m taking a huge risk, but I started doing blocks from Qbank and my cumulative was quite disappointing  so, changed the plan .... but I`m planning to do two blocks from qbank everyday after I finish U/W ... too far-fetched I know ... but let`s see ....
I wish I started my prep a few mnths earlier ... could be a part of a great team ... good going you guys ... love the spirit...
Who knew micro ud take so much time
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| mytime
Kick my butt!
Topics: 39
Posts: 3,174
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The bugs, i suppose?
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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yup ... and guess what , I `m still wavering b/w going thru them all over again and moving on to some other subject ... wish I didn have to go to class today  ...
will finish the remainder of pharma and B/S today after I do microbial genetics and cases ....
Good luck mytime, study hard and drop by when you get time ur avatar makes my day
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| Clozapine
Forum Elite
Topics: 15
Posts: 167
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It`s been such a bad day ... tried to finish metabolism but still left with heme and nucleoprotein and lipid metabolism ... spent three good hours after some mindless assignment ... I just envy the people who get a 4/5 month block absolutely free of work and worries and whatever .... i know i cant afford to be a weakling ... just hope i`m not underestimating the boards ... good luck and goodnight everyone...
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