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A 24-year-old professional gardener comes to the office

because of a generalized, maculopapular, itchy rash that developed a few

days ago. The itching is keeping him awake at night. Three weeks ago he

began treatment for a seizure disorder with 400 mg of phenytoin,( Dermatological manifestations sometimes accompanied by fever have included scarlatiniform or morbilliform rashes. A morbilliform rash (measles-like) is the most common; other types of dermatitis are seen more rarely. Other more serious forms which may be fatal have included bullous, exfoliative or purpuric dermatitis, lupus erythematosus, Stevens-Johnson syndrome and toxic epidermal necrolysis (see Precautions).) daily.

Physical examination now shows a generalized maculopapular rash with

excoriations. The most appropriate management at this time is

discontinuation of the drug and addition of which of the following?

A) Oral hydroxyzine

B) Oral prednisone

C) Topical betamethasone Betamethasone is used to treat the itching, redness, dryness, crusting, scaling, inflammation, and discomfort of various skin conditions<?xml:namespace prefix = o ns = "urn:schemas-microsoft-com:office:office" />

D) Topical emollients
E) Topical hydrocortisone for the temporary relief of (1) minor skin irritations, itching, and rashes caused by eczema, insect bites, poison ivy, poison oak, poison sumac, soaps, detergents, cosmetics, and jewelry; (2) itchy anal and rectal areas; and (3) itching and irritation of the scalp. It is also used to relieve the discomfort of mouth sores







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