doc_clotaire Forum Guru

Topics: 159 Posts: 1,303
| | 01/11/07 - 06:33 PM  
 
|   #1 |
A 45 yo woman presents to a physician with marked swelling of her hands . Five years previously , she had developped multiple arthralgias and early rheumatoid arthritis was suspected . However , no confirmatory inmunologic studies had been perfored at that time . Since then , she has experienced difficulty swallowing and mild dysnea on exertion . On PE , the hands are strikingly swollen , producing a sausage -like appearance to the fingers . Other findings include erythematosous patches over the knuckles , a mild malar rash and slight violaceous discoloration of the eyelids . No joint deformity is noted , although many joints are tender . A chest X-Ray film demonstrate diffuse intestitial infiltrates . In antibody studies , high titers of antibodies directed against which of the following antigens will most likely be present . a ) c - ANCA b ) ds DNA c ) p- ANCA d ) SCL-70 e ) Anticentromere f ) RNP g ) ANA
___________________ The elevator to succes is broke ,you must take the stairs
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| prathapdoctor Forum Elite
Topics: 12 Posts: 406
| | 01/11/07 - 06:51 PM  
 
|   #2 |
its looking like a mixed connective tissue disease to me,so i will go with RNP.
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| MDcooper Forum Guru
Topics: 211 Posts: 470
| | 01/11/07 - 06:54 PM  
 
|   #3 |
i will go with RNP.features of SLE and scleroderma .
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| robin082006 Forum Hero

Topics: 471 Posts: 5,123
| | 01/11/07 - 07:39 PM  
 
|   #4 |
yes mixed connective tissue disease----->F
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| CocaCola Forum Guru

Topics: 35 Posts: 907
| | 01/11/07 - 07:46 PM  
 
|   #5 |
F - RNP
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| doc_clotaire Forum Guru

Topics: 159 Posts: 1,303
| | 01/12/07 - 01:54 PM  
 
|   #6 |
Very good guys , every body got it
___________________ The elevator to succes is broke ,you must take the stairs
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