babydoc4usmle
Forum Guru
Topics: 18
Posts: 634
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decrease in filtration pressure?
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| Ancylostoma
Forum Guru
Topics: 42
Posts: 637
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lol, sorry was taking a break and watching a little tv. Its because she is so dehydrated that she has a increased protein concentration . This means increased glomerular colloid osmotic pressure and this is a force that opposes filtration and thus decreases GFR. I'm surprised your the only one who tried. why did you think a decrease in filtration pressure ?
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| Luckyall
Forum Guru
Topics: 11
Posts: 593
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Correct, i was also thinking abt this , quite a while ago , as a potential Qs 
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| babydoc4usmle
Forum Guru
Topics: 18
Posts: 634
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ok, SMART DUDES
let me ask you this
i need to know if my reasoning is correct or i miss part of a concept
there was a question in K LN about man living @ hight altitude for 2 months and the question is what kind of changes you can expect in his blood i 2 months
among choices there were 2 i was considering:
-increase in Htc
-increase in erythropoetin
i chose E, but it was not correct (Hct was)
could you tell me why?
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| Luckyall
Forum Guru
Topics: 11
Posts: 593
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there is an incr level of circulating erythropoietin, but i feel a more complete answer is wht happens NEXT, as a consequence of it:
incr circulating level of Erythrop--> incr NUMBER of RBCs--> adaptive polycythemia, a different way to say it is incr Hct, since Hct is VolRBCs/Plasma Vol
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| Luckyall
Forum Guru
Topics: 11
Posts: 593
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Besides, you can easier see a Hct level in his BLOOD WORK, is such a common test !!!!!!!!!
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| Ancylostoma
Forum Guru
Topics: 42
Posts: 637
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I dont really have much to add, people living in high altitude are know to having a high HCT. This of course is caused by erythropoeitin secretion do to the relative hypoxia they experience at those altitiudes. Seems like therr looking for the best answer like luckyall explained.
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| babydoc4usmle
Forum Guru
Topics: 18
Posts: 634
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see?????? i always ake the wrong one...but in the explanation they even didn't mention E, even thought increase in E is primary
what if there is abnormal response in Pt to E, then there will be no incr in Hct, but E still be incr...
i knew it....
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| Ancylostoma
Forum Guru
Topics: 42
Posts: 637
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Yeah and in that case you may be right, I think the key is two months, hes been living there for two months so they way us to understand the connection of acclimitization and elevated hematocrit. I actually think I did a question before with a time periods as a week and for that one the answer was elvated erythropoetin. You cant get them all
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