dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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For each numbered biochemical description of an extracellular matrix molecule or its receptor, choode the most appropriate lettered molecule. Answers may be used once, more than once, or not at all
a) collagen
b) fibronectin
c) laminin
d) chondroitin sulfate
e) heparan sulfate
f) hyaluronic acid
g) integrin
h) elastin
i) fibrillin
1) this molecule is composed of subunits assembled into a cruciform aggregate. It binds to heparan sulfate, proteoglycan and type IV collagen. It is an essential structural component of many basement membranes
2) this molecule is glycosaminoglycan that has a MW=1,000,000 or more. It forms the backbone of cartilage proteoglycan aggregates
3) this molecule typically has approximately 1/3 of its amino acids as glycine and is also rich in proline. In some cases, it forms striated fibrillar aggregates
4) this molecule forms anastomosing molecular chains. Upon hydrolysis, it releases the unusual amino acid desmosine
5) this molecule is an important cell adhesion protein. It has MW=460,000 and contains 2 separate polypeptides chains of MW=230,000 cross-linked by -S-S- bridges
6) this molecule is heterodimeric transmembrane glycoprotein. Different forms exist for recognition of fibronectin and laminin
7) this molecule is glycosaminoglycan with a repeating disaccharide containing N-acetyl-D-galactosamine and D-glucuronic acid
8) this is most abundant protein in human body
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| Huntseatchick
Forum Junior
Topics: 11
Posts: 52
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Oh, this one is tough ...
1 -- c
2 -- f
3 -- a (I'm going to begin waitressing at a truckstop if that's not collagen)
4 -- don't know
5 -- h?
6 -- g
7 -- d?
:? -- a
___________________
Do not worry about your difficulties in mathematics. I can assure you mine are still greater. -- Albert Einstein
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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hey u did pretty good 
Correct answers are:
1) c: laminin
2) f: hyaluronic acid
3) a: collagen (u wont be a waiter at a cheap place or not)
4) h: elastin
5) b: fibronectin
6) g: integrin
7) d: chondrotin sulfate
8) a: collagen
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