webjeee
Forum Guru
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10) A 28-year-old woman is diagnosed with lupus nephritis, World Health Organization (WHO) type IV. She has a malar rash, diffuse arthritis, and edema. Her blood pressure is 190/110 mm Hg. Her creatinine is 2.1 mg/dL with a blood urea nitrogen of 28 mg/dL. Her urine reveals 25 red blood cells per hpf, and 3+ protein. One red blood cell cast is seen. A 24-hour urine collection reveals a protein of 11 grams with a creatinine of 1 gram. Which of the following would be the most appropriate management?
A. Oral azathioprine
B. Oral cyclophosphamide
C. Oral gold
D. Oral prednisone
E. Pulse IV cyclophosphamide
Got a free qbank from internet, not sure about the accuracy of its answer.
Anybody knows where is coming from? Kaplan?
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| equinoxe
Topics: 15
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D? not sure about the origin of the q
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| MDcooper
Forum Guru
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this is type 4 so we give iv prednisone+cyclophosphamide.as there is no role of oral drugs in aggressive lupus.For all types,we use prednisone.for 3,4,5 we use cyclophosphamide and prednisone.IV pulse cyclophosphamide is the only option that seems right here
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live and let live.
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| robin082006
Forum Hero
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E, this is acute crisis of SLE.
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| webjeee
Forum Guru
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MDCooper,
what are the treatment for all these types of LN?
thanks,
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| MDcooper
Forum Guru
Topics: 211
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type 1 and 2 dont need any treatment
type 3,4 IV prednisone and for aggressive disease cyclophpsphamide...This is according to UW.while on the internet they say for 1,no treatment,3,4,5 prednisone and cyclophosphamide,I am sticking to UW.
In this particular q,as there is only one IV option,so I picked that.I am not sure if it is correct.
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live and let live.
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