drbcshah
Forum Elite
Topics: 48
Posts: 227
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HIV proteins and function
1- Gag: Viral core protein P17, P24
2-Pol: Protease, integrase, reverse transcriptase, RNAse H
3- Env: gp 120, gp41
4- Tat: Transcriptional transactivator( > gene expression); essential for replication.
5- Rev: transition from early to late gene expression; protein transport from nucleus to cytoplasm; essential for replication.
6- Nef: Transcrpitional silencer; may produce latent infection.
7- Vif: Viral infectivity gene; cell to cell transmission
8- Vpu: Viral protein U; viral particle export.
9- Vpr: Viral protein R; activates viral and cellular promoters
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