robin082006
Forum Hero
Topics: 471
Posts: 5,123
|
Ms. Parker, a 46-year-old bank executive, is referred by her dentist. She had complaints of swollen and bleeding gums for 6 weeks. She appears pale and complains of feeling weak. She smokes half a pack of cigarettes and drinks socially. Her family history is not significant. Her vitals are stable and she is afebrile. CBC reveals:
WBC 44,100mm3
Hemoglobin 10.0
Hematocrit 32%,
Platelets 16,000mm3
The leukocyte distribution is as follows
Blast forms 79%
Promonocytes 12%
Monocytes 8%
Lymphocytes 1%
Cytochemical tests are ordered and they are as under:
Sudan Black Slightly positive
Alpha-naphthyl esterase Positive
PAS reaction Negative
What is the most probable diagnosis?
A. Acute myeloblastic leukemia with maturation
B. Acute promyelocytic leukemia
C. Acute lymphoblastic leukemia
D. Acute erythro leukemia
E. Acute monocytic leukemia
___________________
The Key to Succeed is Patience.
|
| drashishmahajan
Forum Senior
Topics: 6
Posts: 92
|
E....
blast--79%--so its a ac leukemia
slightly positive sudan--cannt be the option B
promonocytenmonocytes present ---Digugilmo syndrome--tht cause bleeding gums
|
| Guptashutosh
Forum Elite
Topics: 35
Posts: 354
|
i think its ALL
|
| drreddy
Forum Newbie
Topics: 1
Posts: 3
|
ALL is seen in children
|
| Geroo
Forum Guru
Topics: 114
Posts: 799
|
Acute monocytic leukemia
|
| krsna
Forum Senior
Topics: 1
Posts: 211
|
INFILTRATION OF GUMS IS COMMON WITH MONOCYTIC SUBTYPES OF AML- M4 AND M5
|
| studying hard
Forum Junior
Topics: 5
Posts: 11
|
m5 is alpha napthyl esterase positive,
so i think monocytic leukemia
|
| robin082006
Forum Hero
Topics: 471
Posts: 5,123
|
yes, answer is E
___________________
The Key to Succeed is Patience.
|
| snowdrops
Forum Senior
Topics: 6
Posts: 149
|
If this question is on my test, it definitely gets me.
I have to go back to my book to check the information to answer this question.
Here is the information on my note book:
M2, acute myeloblastic leukemia: myeloblast increase in blood.
M3, acute promyelocytic leukemia: has Auer rods and DIC.
M4: CNS involvement.
M5, acute monocytic leukemia: gingival hyperlasia and alpha-naphthylesterase test positive.
M6, acute erythroleukemi: erythroblasts.
So, the answer is E, M5.
|
|
| |
| | | | | | | | | |
Similar forum topics