what to do
Forum Senior
Topics: 29
Posts: 88
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guys, if you haven't seen my post in pathology, sorryt o bother you again, plz someone can help me with biochem as well? i need the answers
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47. The anticodon of yeast serinyl-tRNA is 5´-AGC-3´. Which of the following is most likely to be a serine codon?
A ) 5´-ACG-3´
B ) 5´-CCG-3´
C ) 5´-GCU-3´
D ) 5´-UAG-3´
E ) 5´-UCG-3´
14. Double-stranded DNA can be denatured by heating and renatured by cooling. Renaturation under conditions of high stringency has which of the following effects?
A ) Considerable base mismatching is permitted
B ) GC base pairing is inhibited
C ) GT base pairing is promoted
D ) Mismatched DNA hybridization is prevented
21. A 25-year-old woman has had generalized bone pain for 9 years. She has frequent episodes of loose bulky stools. Examination shows muscle weakness and a distended abdomen. X-ray films show generalized demineralization of bones, absence of the lamina dura, and fracture-like lines in the bones of the feet. Which of the following sets of findings in serum is most likely in this patient?
Calcium Phosphorus Alkaline
phosphatase Parathyroid
hormone
A ) ↓ ↓ ↑ ↑
B ) ↓ ↑ ↑ ↓
C ) ↓ ↑ ↑ ↑
D ) ↑ ↓ ↓ ↓
E ) ↑ ↓ ↓ ↑
23. In gout, hyperuricemia resulting from overproduction of urate is most likely to result from a lack of feedback inhibition by ADP or GDP at which enzyme?
A ) Adenosine deaminase
B ) Dihydrofolate reductase
C ) Glucose 6-phosphate dehydrogenase
D ) Nucleotide phosphorylase
E ) Phosphoribosylpyrophosphate synthetase
7. In mucolipidosis II (I-cell disease), the enzyme catalyzing formation of mannose 6-phosphate, the signal for transfer to lysosomes, is missing. Proteins destined for the lysosome are most likely to be found in which of the following locations in patients with this disease?
A ) Endoplasmic reticulum
B ) Extracellular space
C ) Golgi complex
D ) Mitochondria
E ) Nucleus
22. The nucleotide sequence encoding four amino acids near the amino terminus of a 10- kd protein is 5´- ACT GAT TGC GTT -3´. This sequence is mutated by insertion of a single nucleotide (A) in the second codon and becomes 5´- ACT GAA TTG CGT -3´. Which of the following consequences of this mutation is most likely?
A ) Altered cell-cycle checkpoint
B ) Decreased rate of transcription
C ) Protein truncation
D ) Single amino acid substitution
plz, can somene give me answers. i would be really grateful to get the answers.
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saif
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| NE
Forum Guru
Topics: 53
Posts: 504
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47-C
14-D
21-A
23-E
7-C
22-C
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| johnnyu041
Forum Junior
Topics: 2
Posts: 48
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wouldnt 22 be D? protein truncation would happen only if the new codon was a stop codon, UAA, UGA and UAG....
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| Dinie
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Answer to 7, is it B (ECF) since enzymes are found in serum?
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| johnnyu041
Forum Junior
Topics: 2
Posts: 48
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Dinie you are right it is B. but im not sure you have the reasoning correct....in I cell disease there is a failure of phosphorylation of certain mannose residues in newly formed proteins destined to go to the lysosome....without the phosphorylation of these residues instead of going to the lysosome the proteins will be secreted into the extracellular space....
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| Ancylostoma
Forum Guru
Topics: 42
Posts: 642
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I agree with johnny, 22 is d. and both of you guys on 7, its B
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| armaan0101
Forum Newbie
Topics: 0
Posts: 18
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Hey I beg to differ
21. Answer C. Vitamin D deficiency unlikely at this age, more likely to be primary hyperparathyroidism. Anyone wants to give a better explanation............ or correct me if I am wrong?
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| armaan0101
Forum Newbie
Topics: 0
Posts: 18
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Answer to 7 is B (proteins destined for lysosomes are released from gogli complex into ECF.
22 D (forms a stop codon)
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| Palaniappan
Forum Senior
Topics: 30
Posts: 148
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Hey..I think VIT-D deficiency is not due to dietary deficiency but due to malabsorption ..based on the history ..I suppose
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| bd2005
Forum Newbie
Topics: 7
Posts: 24
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47. The anticodon of yeast serinyl-tRNA is 5´-AGC-3´. Which of the following is most likely to be a serine codon?
A ) 5´-ACG-3´
B ) 5´-CCG-3´
C ) 5´-GCU-3´
D ) 5´-UAG-3´
E ) 5´-UCG-3
Answer: C
21. A 25-year-old woman has had generalized bone pain for 9 years. She has frequent episodes of loose bulky stools. Examination shows muscle weakness and a distended abdomen. X-ray films show generalized demineralization of bones, absence of the lamina dura, and fracture-like lines in the bones of the feet. Which of the following sets of findings in serum is most likely in this patient?
Calcium Phosphorus Alkaline
phosphatase Parathyroid
hormone
A ) ↓ ↓ ↑ ↑
B ) ↓ ↑ ↑ ↓
C ) ↓ ↑ ↑ ↑
D ) ↑ ↓ ↓ ↓
E ) ↑ ↓ ↓ ↑
Answer:B
23. In gout, hyperuricemia resulting from overproduction of urate is most likely to result from a lack of feedback inhibition by ADP or GDP at which enzyme?
A ) Adenosine deaminase
B ) Dihydrofolate reductase
C ) Glucose 6-phosphate dehydrogenase
D ) Nucleotide phosphorylase
E ) Phosphoribosylpyrophosphate synthetase
Answer: A
7. In mucolipidosis II (I-cell disease), the enzyme catalyzing formation of mannose 6-phosphate, the signal for transfer to lysosomes, is missing. Proteins destined for the lysosome are most likely to be found in which of the following locations in patients with this disease?
A ) Endoplasmic reticulum
B ) Extracellular space
C ) Golgi complex
D ) Mitochondria
E ) Nucleus
Answer: B
22. The nucleotide sequence encoding four amino acids near the amino terminus of a 10- kd protein is 5´- ACT GAT TGC GTT -3´. This sequence is mutated by insertion of a single nucleotide (A) in the second codon and becomes 5´- ACT GAA TTG CGT -3´. Which of the following consequences of this mutation is most likely?
A ) Altered cell-cycle checkpoint
B ) Decreased rate of transcription
C ) Protein truncation
D ) Single amino acid substitution
Answer: C
Thanks,
bd200004@yahoo.com
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bd200004@yahoo.com
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| laura81
Forum Elite
Topics: 32
Posts: 175
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why is it C for question 22...its no StOP codon there..
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| sukhs
Forum Senior
Topics: 13
Posts: 169
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i guess
c
d
b
e
b
c
these are my answers
correct me if wrong
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| qumsieh
Forum Newbie
Topics: 1
Posts: 15
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That's absurd! 23 is not A. Its E !
Ross University Graduate
Massachusetts General Hospital
Harvard College
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