Guptashutosh wrote:
F heparin ,
sounds like she has some underlying crhronic infl dis ,antiphospholipid syndrom(low platlet,repeated 2nd trim abotrtion)though neutropenia not sig, or something , thats why she is having repeated 2nd trim abortion
no evidence of syphilis xpt vdrl which may be pos in chr inl des, so no point in giving penicilin
secondly i think shall we go ahead with heparin in the presecnce of neutropenia
sugesstions invited
GL
hello ashutosh bhaiya,
hhhhmmm...Heparin is the answer all other choices are not related....penicillin is given if the mother is suffering from syphilis so as to protect the newborn secondly mother is in a monogamous relationship so it reduces the chances of STDs(though husband can acquire STD by extramarital affair ...he he)...now there is no point in giving reassurance,repeating VDRL or FTA-ABS...we are left with only heparin and aspirin...
cheers!
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| Guptashutosh
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thx guys
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| prathapdoctor
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but my doubt is without confirming the diagnosis how can you treat the case directly,i think we have to repeat VDRL again if it comes positive again then we have to do ANA test then tests for antiphospholipid antibody test,only when it comes positive you can treat the case with heparin and aspirin.
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| star1
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VDRL is not specific for syphilis mean It can be positive withnout syphilis diease while FTA-ABS test is specific for syphilis....................
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| webjeee
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A randomized trial of heparin and aspirin for women with in vitro fertilization failure and aPL antibodies did not show any improvement in pregnancy or implantation rates.176
  Williams Hematology > Part X. Hemostasis and Thrombosis >
Chapter 123. The Antiphospholipid Syndrome Jacob H. Rand, Lisa Senzel
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| sabeen60
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false positive VDRL in APS
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