dxtxpx
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Mother of 8 yr boy brought him to pediatrician for second time in a month. the child appeared to have developed strep throat somewhat similar to one he had previously. The child experienced high fever, and extreme irritability due to his condition. Bacterial cultures grew beta hemolytic Strep pyogenes. The total level of IgG, IgA and IgM in his serum was only 65 mg/dL. Antibiotics were prescribed to arrrest the bacterial infection
I) Recurrent pyogenic infections experienced by the boy, along with his low overall serum immunoglobulin level suggests
a) persistent infections by drug-resistant bacteria
b) an immunodeficiency
c) mother is a carrier of bacteria
d) misdiagnosis of earlier infections
e) age related immunodeficiency
II) A disease which results in markedly reduced levels of all immunoglobulins is
a) Bruton's agammaglobulinemia
b) DiGeorge synd
c) Wiskott Aldrich synd
d) Ataxia telangectasia
e) Chediak Higashi synd
III) Defective gene causing this diseae is located on which chromosome
a) chromosome # 13
b) chromosome # 18
c) chromosome # 20
d) X chromosome
e) Y chromosome
IV) Basis of low total immunoglobulin is a
a) T cell def(deficiency)
b) B cell def
c) complement def
d) phagocytic def
e) diseaser acquired def
V) Tx of pt, in addition to antibiotics, would include
a) passive immunization
b) active immunization
c) transfusions
d) immunosuppressive drugs
e) cytokine administration
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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its bruton's X linked hypogammaglobulinemia
1.b
2.a
3.d
4.b
5.b
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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All the answers u gave are correct  except for the last one
V) a) passive immunization
One treatment used in cases of agammaglobulinemia is pooled gamma globulin. This form of passive immunization provides the infant with higher levels of mixed antibody, some of which may cross react with a variety of commonly occuring pathogens, resulting in a reduction of infections. The genetic nature of disease currently precludes any permanent cure. Future advances in gene therapy may one day provide alternative approaches
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| asmi
Forum Hero
Topics: 1043
Posts: 4,609
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oops it was by mistake i clicked b ,but i meant a
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