smal
Forum Guru
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a pt with +PPD is given INH and Vit B-6.he devlops hepatitis.
whats hepatitis due to.
guys this is given in USMLE practice CD.
it said the ans is INH induced hepatitis.but arent we giveing pyridoxine simultaneously!
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| NE
Forum Guru
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You don't prescribe B6 with INH to prevent hepatitis but to prevent neurogical toxicities.
Hepatotoxicity doesn't have a clear mechanism - the most widely accepted theory is that isoniazid metabolism produces reactive metabolites that bind to and damage cellular macromolecules in the liver.
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| fox
Forum Guru
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Agree....Inh causes peripheral neuritis which is prevented by pyridoxine. It cant prevent hepatitis.
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| girl^interrupted
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| virulent
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i agree with you guys
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