drpkaur
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Cystic fibrosis infertility affects both men and women.
Male:
At least 97% of men with cystic fibrosis are infertile.
These men make normal sperm but are missing the tube (vas deferens) which connects the testes to the ejaculatory ducts of the penis. Many men found to have congenital absence of the vas deferens during evaluation for infertility have a mild, previously undiagnosed form of CF.
Female:
The exact incidence of infertility in adult females with CF is not known but is thought to be about: 20%.
The anatomy of their reproductive tract is perfectly normal, but thick mucus prevents the sperm from fertilizing the egg.
Advanced respiratory disease and poor nutrition also contribute to the decreased fertility; malnutrition disrupts ovulation and causes amenorrhea.
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