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Kaplan Qbank USMLE



Author3 Posts
  #1

Chief cause of rigor mortis is:

a) decline in ATP production
b) decreae in muscle temperature
c) decrease in muscle Ca+2
d) release of lysosomal enzymes
e) death of neuromuscular junctions

  #2

decline in atp production

  #3

Correct

When a person dies, initially, their muscles become rigid (rigor mortis). Death results in cessation of respiration. Consequently, ATP is no longer formed. The binding of SF 1 of myosin to actin is irreversible when there is no ATP present. During normal contraction, ATP binding to SF 1 releases the myosin cross bridge from the actin. Without ATP, cross bridges remains firmly bounf. Later, the lysosomal enzymes present in muscle tissue are released, causing a degredation of the muscle proteins leading to a loss of rigor mortis.







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