ManuNastai
Transilvanian..
Topics: 55
Posts: 838
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38.
A 68-year-old man has heterozygous familial hypercholesterolemia. Which of the following agents will decrease plasma VLDL and LDL concentrations but will cause cutaneous vasodilation that subsides with repeated doses?
A ) Niacin
B ) Nitric oxide
C ) Prostacyclin (PGI2)
D ) Prostaglandin E2
E ) Substance P
F ) Thyroxine (T4)
G ) Vasoactive intestinal polypeptide
H ) Vitamin B6 (pyridoxine)
40. A 27-year-old man with recurrent peptic ulcer disease has a small pancreatic neoplasm that produces large amounts of gastrin. While awaiting operation, the patient should be treated with
A ) chenodeoxycholic acid
B ) methacholine
C ) metoclopramide
D ) omeprazole
E ) sucralfate
50. A 23-year-old woman is scheduled to undergo surgical repair of an aortic malformation. A ganglionic blocking agent is administered before the procedure to decrease her blood pressure. The hypotension is achieved by binding of the drug at which of the following receptors?
A ) α1-Adrenergic
B ) α2-Adrenergic
C ) β1-Adrenergic
D ) β2-Adrenergic
E ) Muscarinic
F ) Nicotinic
RENAL/Pharma
47. A 40-year-old woman has recurrent calcium-containing renal calculi. Which of the following strategies is most likely to decrease her risk for forming additional calculi?
A ) Administration of a thiazide diuretic
B ) Alkalinization of the urine
C ) Ingestion of a high-oxalate diet
D ) Ingestion of a high-protein diet
E ) Restriction of fluid intake
PHARMA/PHYSIO
50. A 23-year-old woman is scheduled to undergo surgical repair of an aortic malformation. A ganglionic blocking agent is administered before the procedure to decrease her blood pressure. The hypotension is achieved by binding of the drug at which of the following receptors?
A ) α1-Adrenergic
B ) α2-Adrenergic
C ) β1-Adrenergic
D ) β2-Adrenergic
E ) Muscarinic
F ) Nicotinic
14. A 25-year-old woman at 32 weeks' gestation begins taking a drug to delay the onset of preterm labor. After the first dose, she notices tremulousness in her hands. Which of the following types of receptors is most likely to be involved in this effect?
A ) α1-Adrenergic
B ) β2-Adrenergic
C ) Dopaminergic (D1)
D ) Muscarinic (M1)
E ) NMDA
44. An asymptomatic 42-year-old man with essential hypertension is started on an angiotensin-converting enzyme inhibitor. Which of the following shows the most likely effect of treatment on circulating levels of aldosterone, renin, and bradykinin?
Aldosterone/Renin/Bradykinin
A) ↓ ↓ ↓
B) ↓ ↓ ↑
C) ↓ ↑ ↑
D) ↑ ↑ no change
E) ↑ ↑ ↑
F) ↑ ↑ ↓
25. A series of experiments is performed to determine the mechanism by which a pharmacologic agent traverses cell membranes and accumulates within target cells. The rate of transport depends on the concentration of the drug only. When the extracellular concentration of the agent exceeds 10 mM, no further increase in the rate of uptake is observed. Structurally similar compounds pass through the cell membrane, but at a lower rate. Ouabain, an inhibitor of Na+/ K+ ATPase, fails to inhibit transport. Which of the following is the most likely mechanism by which this agent enters cells?
A) Antiport
B) Facilitated diffusion
C) Ion-gated coupling
D) Simple diffusion
E) Symport
___________________
"Love is the only inflamation of the heart that drains in the vagina" (translation after Dr Petre Florescu, Professor of Pathology, UMF "Iuliu Hatieganu", Cluj Napoca
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| ManuNastai
Transilvanian..
Topics: 55
Posts: 838
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my answer:
38. A
40. D
50. F
47. A
14. B
44. C
25. B
___________________
"Love is the only inflamation of the heart that drains in the vagina" (translation after Dr Petre Florescu, Professor of Pathology, UMF "Iuliu Hatieganu", Cluj Napoca
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| nish3123
Forum Newbie
Topics: 1
Posts: 15
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why is 14 B ? any explanations? thought it was C hmm plz explain thanks
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| Ancylostoma
Forum Guru
Topics: 42
Posts: 642
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b2 agonist can be used to relax uterine musculature. It is another place that b2 receptors are found.
Im agreed with manu answerd.
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