 |  5 NMBE Qs8
|
|
| Author | 3 Posts |
ManuNastai
|
40. The sulfonylureas exert their hypoglycemic effect by blocking which of the following channels?
A ) Ca2+
B ) Cl–
C ) K+
D ) Mg2+
E ) Na
46. A full-term 1-week-old male neonate with a craniofacial deformity and pulmonary hypoplasia has not produced urine. Labor and delivery were uncomplicated. His mother has hypertension and took various promotional samples of antihypertensive medications throughout the pregnancy. Which of the following antihypertensive drugs most likely caused the abnormality?
A ) Atenolol
B ) Diltiazem
C ) Enalapril
D ) Hydrochlorothiazide
E ) Methyldopa
F ) Verapamil
47. A 65-year-old woman develops a proximal deep venous thrombosis 1 week after an elective total hip replacement. What is the mechanism of intravenous heparin in treating this disorder?
A ) Activation of plasmin
B ) Facilitation of inactivation of thrombin by antithrombin III
C ) Inhibition of activation of tissue plasminogen
D ) Inhibition of vitamin K-dependent coagulation factors
E ) Reversible inhibition of protein C and protein S activity
49. After taking an overdose of propranolol, a 35-year-old woman develops sinus bradycardia and syncope. In order to stimulate the same second messenger system that is activated by β-adrenergic receptors, which of the following drugs will be most effective to increase her heart rate?
A ) ADH (vasopressin)
B ) Atrial natriuretic peptide
C ) Clonidine
D ) Glucagon
E ) Phenylephrine
9. Which of the following antimicrobial agents is most likely to be administered orally for the treatment of potentially serious systemic infections because of its predictable bioavailability?
A ) Amphotericin B
B ) Ciprofloxacin
C ) Gentamicin
D ) Polymyxin B
E ) Vancomycin
|
| NE
Forum Guru
Topics: 53
Posts: 504
|
40- C-sulfonylureas close K channel in beta cells
46- ACE are contraindicated in pregnancy because they can interfere with fetus's kidney development.
47- B - Heparin binds to the enzyme inhibitor AT-III causing a conformational change which results in its active site being exposed. The activated AT-III then inactivates thrombin . The rate of inactivation of these proteases by AT-III increases 1000-fold due to the binding of heparin.
49 - D- glucagon actions on the rec in gear with Gs
9- cipro is the only drug from the list with oral bioav.
|
| ManuNastai
|
thanks
|
|
| |
| | | |
You don't have permission to post.
|
