 |  5 NMBE Qs3
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| Author | 2 Posts |
ManuNastai
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12. A 54-year-old woman with type 2 diabetes mellitus well controlled with oral hypoglycemic agents comes to the physician because of a 2-week history of swelling in her left knee. She tells the physician that her knee is very stiff when she awakens in the morning and at bedtime. The pain and stiffness worsen with exertion. Low-dose ibuprofen results in incomplete relief. Which of the following best explains why a larger dose of ibuprofen is more appropriate?
A) The anti-inflammatory dose is nearly twice the analgesic dose
B) The drug is excreted at a fast rate because of renal complications of diabetes mellitus
C) Increasing the dose extends the half-life of the drug
D) Menopausal women metabolize the drug at a faster rate than premenopausal women
E) Oral hypoglycemic agents interfere with protein binding of ibuprofen
26. A 37-year-old man develops a spiking fever in the intensive care unit after an operation to control an abdominal hemorrhage. Evaluation does not show a focal infection. Therapy with a broad-spectrum cephalosporin is initiated. After 3 days of antibiotic therapy, the patient has abdominal pain and profuse watery diarrhea. Examination of stool for ova and parasites is negative. Stool tests positive for Clostridium difficile antigen. The most appropriate therapy is
A) amphotericin
B) erythromycin
C) metronidazole
D) penicillin
E) trimethoprim-sulfamethoxazole
27. A 23-year-old woman has prolonged episodes of wheezing, dyspnea, and anxiety that are relieved by β-adrenergic agonists. The major mediator of her condition is
A) bradykinin
B) eosinophil chemotactic factors
C) leukotrienes
D) prostaglandin E
E) thromboxane
28. After several courses of treatment for non-Hodgkin's lymphoma, a 33-year-old man develops gross hematuria. Which of the following drugs is most likely to be responsible for this adverse effect?
A) Carmustine (BCNU)
B) Cyclophosphamide
C) Daunorubicin
D) Methotrexate
E) Vincristine
37. What is the principal site of therapeutic action of aspirin in the diagram of a blood vessel?
a)
b)
c)endothelium
d)serum
e)neutrophil
f)RBC
g) plattelet
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| ManuNastai
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my answers and already agreed on the forum:
12. A
26. C
27. C
28. B
37. G
sorry, didn't see they were discussed
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