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Kaplan Qbank USMLE



Author3 Posts
  #1

7. A 10-year-old boy with asthma has been receiving oral hydrocortisone daily in increasing doses for the past 2 years. He is obese and has growth retardation and edema of his lower limbs. Which of the following is the most likely explanation for the edema?

A ) The drug binds to both glucocorticoid and mineralocorticoid receptors

B ) The drug is converted to a mineralocorticoid in the liver

C ) Pulmonary production of angiotensin is increased

D ) Renin activity is increased because of stress

E ) Secretion of ADH (vasopressin) is increased because of stress




8. Eight hours after ingesting 30 g of acetaminophen in a suicide attempt, a 17-year-old boy is admitted to the hospital with nausea and vomiting. If left untreated, the complication most likely to develop in this patient is

A
) cardiac arrhythmia

B
) gastrointestinal bleeding

C
) hepatic necrosis

D
) respiratory depression

E
) tonic-clonic seizures


12. A patient who is taking probenecid is expected to have an increased excretion of which of the following?

A ) Cephalosporin

B ) Creatinine

C ) Penicillin

D ) Tetracycline

E ) Urate



21. An obese 44-year-old man with type 2 diabetes mellitus is unable to achieve appropriate glycemic control with diet and exercise. The physician consequently prescribes a sulfonylurea. This class of drugs promotes the release of insulin from pancreatic β cells through which of the following factors?

A ) Inhibition of ATP-sensitive K+ channels

B ) Inhibition of Na+–K+ ATPase

C ) Inhibition of voltage-sensitive Ca2+ channels

D ) Stimulation of guanylylate cyclase

E) Stimulation of phosphodiesterase


26. Which of the following drugs produces vasoconstriction that is not blocked by prazosin and bradycardia that is blocked by scopolamine?

A ) Amphetamine

B ) Angiotensin

C ) Norepinephrine

D ) Phenylephrine


  #2

7-A
8-C
12- E
21-A
26-B

  #3

great, thanks







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