DrVirgo
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16. A 67 year old woman with a history of schizophrenia and type 2 DM has been maintained on thioridazine for years. She recently had a myocardial infarction and was diagnosed with Mobitz thpe II block. Her physicial now wants to change her antipsychotic medication. Which of the following is the most appropriate pharmacotherapy?
A. Olanzapine
B. Pimozide
C. Quetiapine
D. Risperidone
E. Ziprasidone
Explain why please! 
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| yasmeen
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RISPERIDONE? OLANZAPINE CAUSES PANCREATITIS AND TYPE2 D.M
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| npas
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[c]..out of all Quetiapine boasts of the least "absolute" Contraindication..Olanzapine precipitates Diabetic ketoacidosis in DM patients..Risperidone and Ziprasidone can cause av blocks..this patient already has one.Pimozide is cardiotoxic..can cause qt prolongation and cardiac arrhythmias..
Quetiapine should also be used with caution coz it has a tendency to cause hypotension.Since there is no absolute CI I will go for this drug in this patient.
Plz let me know ur answer.
gl
npas
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| DrVirgo
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C is right.
Thanks for the explanation!
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