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Vd, Clearance, , half life
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Author3 Posts
  #1

A pharamacologist is trying to determine what the plasma concentration of an experimental antimicrobial agent (drug X) will be at steady state. A continuous intravenous infusion of the agent began 4 hours earlier at a rate of 10mg/min. Drug X has a Vd of 100L and a clearance of 0.5L/min. If the rate of infusion remains constant, what will be the plasma concentration at steayd state?

a. 0.1mg/L
b. 2mg/L
c. 10mg/L
d. 20 mg/L
e. 100mg/L

  #2

Dosage= c% plasm. * CL ------ C% = 10 mg/ml /o.5 l/min----20


  #3

yeap...







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