| Author | 5 Posts |
epica
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a 45 yearold woman has an acute coronary occlusion,within seconds, the ischemic region shows mitochondnal swelling and depletion of glycogen granules, Which of the followings metabolic events is the most likely cause of these cellular changes?
a Accumulation of free fatty acids
b ATP depletion
c Degradation of membrane phospholipid
d Efflux of K+
e Influx of Na+
B or C? I copied this debate Q from another forum
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| ssrpk
Forum Fanatic
Topics: 154
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b ATP depletion
as Degradation of membrane phospholipid is an irreversible event, which takes atleast 40 minutes to develop after coronary occlusion, faster if there is reperfusion injury!
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| fox
Forum Guru
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B for sure. Depleted ATP results in the failure of Na/ K pump leading to retention of Na within the cell , which in turn leads to swelling of the organelles by osmotic damage. This is an ex of irreversible injury. Degradation of membrane phospholipid is irreversible injury.
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| yasmeen
Forum Guru
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B IS THE EARLIEST EVENT
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| HILFIGER
Forum Senior
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B
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