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Kaplan Qbank USMLE



Author5 Posts
  #1

someone plz tell me in schillings test if we give IF and no radioactive cobalmine in urine -what does it mean?
A. pernecious anemia
B.ileal malabsorbtion

acc. to my understandignit was A(atrophic gastritis was among the options)
can anyone pls explain me the concept?

___________________
remedy for weakness is not brooding over it ,but thinking of strength.

  #2

could be anything but pernicious anemia. anything that would lead to B12 malabsorbtion

it could be crohn's, enteric infection, cronic pancreatitis, ileal rezection..

___________________
"Love is the only inflamation of the heart that drains in the vagina" (translation after Dr Petre Florescu, Professor of Pathology, UMF "Iuliu Hatieganu", Cluj Napoca

  #3

with schilling's test, you saturate all the transcobalamin in the blood by administering i.v. normal B12, because you want ALL the radioactive labeled B12 that you make the patient to ingest to be excreted in the urine, so you can determin it's presence there.

so, if you administer IF and you find the labeled B12 in the urine, you know that there was a IF deficiency before and you got PA

if you administer antibiotic and after a day or 2 you find labeled B12 in the urine, you know you had a enteric tract infection and you cured it, so that was why you had a B12 def. before

if you administer pancreatic extract and find B12, it's because you had a cronic pancreatitis

___________________
"Love is the only inflamation of the heart that drains in the vagina" (translation after Dr Petre Florescu, Professor of Pathology, UMF "Iuliu Hatieganu", Cluj Napoca

  #4

way too perfect ... atta boy

___________________
life is guud

  #5

thanks manunastri,
u r a gr8 help

___________________
remedy for weakness is not brooding over it ,but thinking of strength.







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