dxtxpx
Forum Guru
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The block of alpha-1 post synaptic receptors by phenoxybenzamine is irreversible and non-competitive; so how does the body overcomes this block?
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| mjl1717
Forum Hero
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By synthesizing new alpha 1 receptors
In this case duration of action is significant-the synthesisize of new alpha one receptors occurs in approximately one day
it will last for at least 24 hours
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| dxtxpx
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excellent explanation 
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