erek Forum Newbie
Topics: 1 Posts: 2
| | 10/27/06 - 02:21 PM  
 
   
 
|   #1 |
i'm trying to understand how an agonist or antagonist is used up after it binds to a receptor. is the chemical used up in a way that affects the processes proceeding the activation of the receptor, or is there something else that happens?
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| NE Forum Guru

Topics: 53 Posts: 504
| | 10/28/06 - 09:39 AM  
 
   
 
|   #2 |
maybe it helps!
Attached Files:
rec agonist.png (146 KB, 30 downloads)

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| NE Forum Guru

Topics: 53 Posts: 504
| | 10/28/06 - 09:40 AM  
 
   
 
|   #3 |
Attached Files:
Res antag.png (215 KB, 17 downloads)

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| NE Forum Guru

Topics: 53 Posts: 504
| | 10/28/06 - 09:40 AM  
 
   
 
|   #4 |
Attached Files:
Res antag.png (208 KB, 9 downloads)

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| erek Forum Newbie
Topics: 1 Posts: 2
| | 10/28/06 - 01:41 PM  
 
   
 
|   #5 |
it does a little bit, as i now understand that the agonist/antagonist and receptor work under a lock and key mechanism, but i still do not know if the chemical agonist is used up in the the processes of the activation of the receptor. does the chemical help fuel the processes or have some kind of functional affect other than activating?
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| Leopard Forum Guru

Topics: 30 Posts: 401
| | 10/30/06 - 01:21 PM  
 
   
 
|   #6 |
Receptor and Ligand complex is internalized and taken up by lysosomes.Then Uncoupling occurs here.Ligand is degraded and receptor recycled back.But not all receptors are recycled back ,some are also degraded.If there is excessive Ligand -receptor coupling then this degradation is enhanced. Best of luck
___________________ FA is just a good revision book.It is not a "real" learning tool.
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