Prep for USMLEPrep for USMLE Forum
   Forum    Step 1  Step 2 CK Step 2 CS Step 3  Match  IMGs Resources Search






Previous Topic | Next Topic  receptor agonists 




 
Kaplan Qbank USMLE



Author6 Posts
  #1

i'm trying to understand how an agonist or antagonist is used up after it binds to a receptor. is the chemical used up in a way that affects the processes proceeding the activation of the receptor, or is there something else that happens?

  #2

maybe it helps!

Attached Files:
rec agonist.png (146 KB, 30 downloads)
attachment
  #3



Attached Files:
Res antag.png (215 KB, 17 downloads)
attachment
  #4



Attached Files:
Res antag.png (208 KB, 9 downloads)
attachment
  #5

it does a little bit, as i now understand that the agonist/antagonist and receptor work under a lock and key mechanism, but i still do not know if the chemical agonist is used up in the the processes of the activation of the receptor. does the chemical help fuel the processes or have some kind of functional affect other than activating?

  #6

Receptor and Ligand complex is internalized and taken up by lysosomes.Then Uncoupling occurs here.Ligand is degraded and receptor recycled back.But not all receptors are recycled back ,some are also degraded.If there is excessive Ligand -receptor coupling then this degradation is enhanced.

Best of luck


___________________
FA is just a good revision book.It is not a "real" learning tool.







You don't have permission to post.




Login or Register to post messages in this topic





















Contact | Leaders | Disclaimer | Privacy

Copyright @ Prep for USMLE. All rights reserved.