fongch
Forum Elite
Topics: 71
Posts: 316
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Usage of which of following drug may cause ventricular fibrillation, and thus is contraindicated, in patients w/ Wolff-Parkinson-White syndrome and atrial fibrillation?
A. Amiodarone
B. Digoxin
C. Adenosine
D. Disopyramide
E. Quinidine
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| NE
Forum Guru
Topics: 53
Posts: 504
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Digoxin may increase the ventricular rate and cause ventricular fibrillation in patients with WPW.
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| Addicudo
Forum Guru
Topics: 124
Posts: 615
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Digoxin has Negative chronotopic effects by slowing Vagal impulse .. and therefore potentially lead to AV Blockadge ...
Thus in a Pt with WPW synd .. where there is an accessory pathway (The Bundle of Kent) .. Impulse conduction increases through the accessory pathway .. leading to a VF.
P.s. Bundle of Kent has a longer refractory period than the AV nodes .. !! therefore allowing the circut pathway .. !!
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... Idle hands are the DeVilS play ground ...
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