linaorvos
Forum Elite
Topics: 47
Posts: 258
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25 yr old woman w/generalized bone pain for 9yrs
has frequent loose bulky stool, exam shows musle weakness,distend abdom. x-ray shows generlized demineralization of bone.
serum finding of the pt. should be:
Ca.Phosphorus.alkaline phospatase.PTH
a.dec,dec,inc,inc
b.dec,inc,inc,dec
c.dec,inc,inc,inc
d.inc,dec,dec,dec
e.inc,dec,dec,inc
anyone please...
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| suravi
Forum Newbie
Topics: 5
Posts: 19
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I think the answer is A. Malabsorption leading to hypovitaminosis D.
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| linaorvos
Forum Elite
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me 2, thanks!
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| ManuNastai
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E
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| ssrpk
Forum Fanatic
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i think its A too, vit-D def. due to fat malabsorption leading to low Ca++ absorption thus low serum Ca++ which iover the span of nine yrs hv been compensated by inc. in PTH! which wud lower the PO4 level as well!
besides if Ca++ were to increase due to excess bone resoprtion why wud PTH increase then, unless its production gets autonomous; which is not the case here!
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| mediocre
Forum Elite
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ok it looks like A, except why shud there be an incrsd ALP????
in malnutrition or incrsd PTH phosphates decrs and so shud ALP
anyone???thanx.
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| ssrpk
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Topics: 154
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alkaline phosphatase hydrolyzes phosphate esters which then depending upon the product of conc. of Ca++ and PO4 either gets into solution or precipitated out!
it is indeed a non-specific indicator of bone turn-over and increases with inc. PTH!; because with ensuing bone loss AP wud be activated to reconstitute the bone mass!
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