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Kaplan Qbank USMLE



Author12 Posts
  #1

A 4-year-old girl has been unable to eat for 2 days because of a gastrointestinal tract disorder. Which of the following is the major source of fuel being oxidized by her skeletal muscle?

A Muscle creatine phosphate

B Muscle glycogen

C Muscle triglyceride

D Serum fatty acids

E Serum glucose

Please explain when you answer. Thank you.

  #2

D

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  #3

grin Agreed with ManuNasti.

  #4

Yup

  #5

Muscle glycogen

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  #6

Fatty acid is right , I think glycogen is already depleted. Same with Creatine-P , it is only reserve of energy for short time.


  #7

raised eyebrow Glycogen would be utilized first and the reserve form of energy creatine phosphate. For further maintainance of energy it would be oxidation of fatty acid.nod

  #8

nod

  #9

kaplan p158

FA and Ketones


  #10

nod muscle uses fa and ketones in starvation


  #11

ya, gycogenolysis serves for energy only for a very short time-12 hrs to 1 day roughly.
then its gluconeogenesis from gluconeogenic AA(which supplies C-skeleton )and ATP from B-oxidation of FA.but this glucose goes to brain and RBCs. rest of the tissues,SM and adipose tissue utilize energy from ketones.liver however gets its energy from B-oxidation(plz correct me if am wrong),as it doesnt 've thiophorase to break down acetoacetate .

Edited by smal on 11/28/06 - 01:04 PM

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  #12

it will be store of muscle glycogen which will serve as major source of fuel for the skeletal muscles during period of starvation and if starvation is further prolonged as the muscle glocogen store depletes muscle proteins start breaking up to aminoacids to make up for the glucose defficiency through gluconeogenesis and this breakdown of muscle proteins is seem in prolonged sstarvation as severe wasting:







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