have fun ;)

Prep for USMLE Forum

» Log in | Register

Forum

Step 1

Match

Prep4USMLE Forum » USMLE Step 1 Forum » Physiology Forum

have fun ;)

Author

4 Posts

fox
Forum Guru
avatar

Topics: 70
Posts: 727

10/14/06 - 02:54 PM

#1
Which of the modifications of an endogenous active peptide can slow the clearance?

A. administering the peptide with an enteric coating
B. Decreasing amino acid number
C. Ensuring a free amino group at the N terminus
D. Ensuring a free carboxyl group at the C terminus
E. substituting a D for an L amino acid

___________________
Aim High

ManuNastai
Transilvanian..
avatar

Topics: 55
Posts: 838

10/15/06 - 12:37 AM

huh?! ugly question!! shocked

E?

___________________
"Love is the only inflamation of the heart that drains in the vagina" (translation after Dr Petre Florescu, Professor of Pathology, UMF "Iuliu Hatieganu", Cluj Napoca

fox
Forum Guru
avatar

Topics: 70
Posts: 727

10/15/06 - 03:28 PM

Thanks for attempting! the only one who attempted out of so many......I to think its E....Sorry..I dont know the right answer nor could I find the reference

___________________
Aim High

ace.speed
Forum Newbie

Topics: 0
Posts: 2

10/17/06 - 09:17 PM

E.
D is a negative charged residue while L is electronically neutral. The introduction of a negative charge will decrease its filtration through renal membrane (negative charged).

You don't have permission to post.