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Author3 Posts
  #1

<13>A 57-year-old man presents to the emergency department with a
nosebleed for the past 2 hours. The patient received a prosthetic
heart valve 5 months ago and is currently taking warfarin (7.5 mg per day)
and oral antibiotics. Laboratory evaluation reveals
an INR (international normalized ratio, the ratio of
patient to normal prothrombin times) of 6.4. Which of
the following antibiotics is the patient most likely taking?
A. Ampicillin
B. Cephalexin
C. Nitrofurantoin
D. Norfloxacin
E. Phenazopyridine

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  #2

D>>

  #3

D
Quinolones inhibit P450 therefore decrease liver metabolism of warfarin and increase plasma levels

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