dxtxpx
Forum Guru
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Posts: 1,233
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Match the lettered expression from the list below with its most appropriate definition in the items below. Answers may be used once, more than once or not at all
a) apparent vol of distribution
b) half-life
c) clearance
d) bioavailability
e) area under the curve
f) minimum therapeutic concentration
g) first pass effect
h) extraction
i) effectiveness
j) phase I reaction
k) phase II reaction
1) this parameter would be most directly and drastically altered in a pt with chronic renal failure
2) this parameter is an expression of time required for a drug concentration to be reduced to 50% of an initial value
3) this parameter will vary depending on the affinity of peripheral tissues for the drug and lipid solubility
4) depends on chemical changes in drug due to chtochrome P450 modification, esp in the liver
5) UDP-glucuronate often involved in this process which increases drug solubility
6) the fraction of drug removed from the circulation of blood thru an organ
7) this parameter is usually less than 1 for orally administered drugs
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| mahendra
Forum Guru
Topics: 173
Posts: 419
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1 C
2.B
3.A
4.J
5.K
6.G
7.D
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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all are correct responses  but u missed #6
correct responses:
1 c
2 b
3 a
4 j
5 k
6 h
7 d
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| mahendra
Forum Guru
Topics: 173
Posts: 419
|
6 .IS IT CLEARANCE? :?:
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
|
I already listed the right answers. plz take a look
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