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Kaplan Qbank USMLE



Author2 Posts
  #1

hb n1 AAGUAUCACUAAGCUCGC and hbncr AAGAGUCACUAAGCUCGCUUUC....UAU UAA HB is isolated from erythrocytes of young child with anemia hb electrophoresis reveals the presence of unstable hb known as hb cranston Hbcr containing an abnormal b-globin chain the normal sepuence of globin gene and globin of Hb cr is presented above which of the following will acount for the formation of Hb cr
1-aframshift mutation resulted in the deletion of several amino acids residues in b chain
2-amutation in the stop codon resulted in prolongation of b-chain
3-apoint mutation resulted in insertion of stop codonin b-chain
4-atwo base pair addition resulted in the elimination of stop codonin the b-chain
5-atwo bsae pair deletion resulted in truncation of the b-chain

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  #2

3?

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