asmi
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K secretion by distal tubules will be decreased by:
A. metabolic alkalosis
B. a high k+ diet
C. spironolactone administration
D. thiazide administration
E. hyperaldosteronism
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| dxtxpx
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choice A :?:
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| asmi
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here answer is C
Since all the others increases K secretion.
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| dxtxpx
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could u care to explain this one detail, thanks
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spironolactone is a k-sparing diuretic,which promotes diuresis by inhibiting the Na-K counter-transport in distal tubule.this transport mechanism promotes Na entry in return for K exit,and spironolactone reverses this process,inhibiting Na entry and K exit into the lumen.so this drug causes decreased K-secretion.
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| dxtxpx
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thanks n how the other choices increase K+ ?
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