dxtxpx
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SE occur with many cardiovascular agents. Match the SE which is best associated with given drug. Answers may be used once, more than once or not at all
a) Amrinone
b) Amiodaron
c) Propanolol
d) Quinidine
e) Lidocaine
f) Procainamide
g) dopamine
h) epinephrine
i) atenolol
j) dobutamine
k) sotalol
l) captopril
m) streptokinase
1) high doses can cause CNS effects, including convulsions
2) Can aggravate diabetes, HF, asthma
3) Cause cinchonism
4) Cause renal artery dilation, increase cardiac output, but increase total peripheral resistance at high doses
5) unusual and long-lived pharmacikinetics, drug deposits in eyes
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| asmi
Forum Hero
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1.e
2c
3.d
4.g
5 b
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| dxtxpx
Forum Guru
Topics: 259
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Right on 
Amiodarone has unusual pharmacokinetics, and depostis in skin and eyes.
Lidocaine has local anesthetic properties, and can cause CNS toxicity. It is otherwise relatively safe.
Cinchonism is specific toxicity of quinidine, whereas, systemic lupus-like effects are seen with procainamide
Noncardioselective beta1,beta2 blockers like propanolol aggravate asthma and DM via beta 2 blockage. Dopamine can greatly increase systemic vascular resistance at high doses. ACEI are generally without serious SE
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| asmi
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yes thus dopamine can increase BP at high doses via action on alpha 1 receptors.
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