sridevibandaru24
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8. A child born without limbs is found to have a mutation in a receptor for a fibroblast growth factor. The absence of limbs most likely resulted from a disruption of the processes controlling which of the following?
A) Apoptosis
B) Differentiation
C) Epithelial-mesenchymal conversions
D) Proliferation
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| smal
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A.
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| allie
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its D...
FGFR3 gene defect causes inhibition of proliferation of chondrocytes in the growth plate which is responsible for short limbs in achondroplasia..
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| klimt
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I go for D too - inhibition of differentiation
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| ManuNastai
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me too
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| Musuq
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thanks allie
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| romodoc
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smal wrote:
A.
Its Actually D, but remember that A apoptosis, is involved in the loss of the thin areas called INTERDIGITAL GROOVES in the hands, this arrangement gives rise to free digits. 
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| MRMAVERICK
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d
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| laura81
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here is a similar question..i think...from usmle CD
kid born with syndactily of index, middle and ring fingers. this presentation is due to the failure of
a. apoptosis
b. proliferation
c. propagation
d. differentiation
and teh answer here is A...whats the difference???
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| jabialaa
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the difference ...
in the first case there is abscence of the limbs because of proliferation defect but in the other case there are limbs but with syndactily
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| lq2006
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Proliferation
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