dxtxpx
Forum Guru
Topics: 259
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With respect to SE of consequence in the elderly, which anti-HT would be most likely to cause significant orthostatic hypotension
a) propanolol
b) clorthiazide
c) atenolol
d) clonidine
e) captopril
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| mahendra
Forum Guru
Topics: 173
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CLONIDINE?
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| dxtxpx
Forum Guru
Topics: 259
Posts: 1,233
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yes in elderly orthostatic hypotension is associated with centrally acting symptholytic agents, making clonidine the right answer
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| asmi
Forum Hero
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WHY CAN'T IT BE E ?
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| dxtxpx
Forum Guru
Topics: 259
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Unlike clonidine which is centrally acting symptholytic drug, balanced vasodialators act to simultaneously dilate arterial and venous systems; nitroprusside is an IV administered balanced vasodilator, while captopril and other ACEI are good e.g. of balanced vasodilators used in outpt tx of CHF. Balanced vasodilators lower preload (venodilation) and afterload (arteriolar dilation). In CHF, this lessens edema by causing venous pooling while simultaneously reducing amount of force needed to maintain adequate perfusion (afterload)
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