sandra
Forum Guru
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what happens to the pO2 of arterial and venous blood in anemia.
from what i understand, arteial po2 remains normal. but what about the venous? i read some where that it decreases. but in anemia, the blood viscosity decreases>>>so cardiac ouput increase(flow increases>>less time for o2 extraction by tissues >>> venous po2 should be more then.
did i go wrong some where? 
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| blueocean
Forum Senior
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I don't think it's about the CO!
In an anemia, DPG production by RBC's is increased to cause a further right shift in the O2 loading/unloading curve so that O2 unloading at the tissues is even more efficient (ie. the body tries to compensate for the loss of O2 carrying capacity by increasing the efficiency of O2 unloading from RBC's at the tissues).
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| sandra
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agreed. so what happens to venous po2?
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| young_doc
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As far as i know, tissue extracts more O2 under anemic conditions (partly due to the increased in 2,3BPG as BlueOcean mentioned). So i would guess that Venous O2 decreases.
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| fox
Forum Guru
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2,3 dpg will affect the SA02 & not the SPo2. In Anemia i think arteriolar spo2 in inc due to compensate the dec in SAO2 due to dec Hb. The venous Spo2 I think will be decreased as the starved tissues extract more O2 from what is dissolved in the blood as they dont get enough O2 from the saturated HB. What do u guyss think?
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