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Author3 Posts
  #1

Pt. with lymphadenopathy & splenomegaly & raised WBC . What is the confirmatory test


-CBC differential

-Bone marrow aspiration



Can it be only differential?



  #2

assuming the pt is an older one, and were thinking of CLL, the bone marrow will not help. hance we'll have to choose differential.

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  #3

Thanks. I found something on emedicine about this

Bone marrow aspiration and biopsy with flow cytometry is not required in all cases but may be necessary in selected cases to establish the diagnosis and to assess other complicating features such as anemia and thrombocytopenia. For example, bone marrow examination may be necessary to distinguish between thrombocytopenia of peripheral destruction (in the spleen) and that due to marrow infiltration.










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