Palaniappan
Forum Senior
Topics: 30
Posts: 148
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Which of the following genes involved in the synthesis of immunoglobulins are linked on a single chromosome?
A. C gene for gamma chain and C gene for alpha chain
B. C gene for gamma chain and C gene for kappa chain
C. V gene for kappa chain and C gene for the epsilon chain
D. V gene for lambda chain and C gene for kappa chain
E. V gene for lambda chain and V gene for heavy chain
This is confusing.anyone can explain the answer better??it would be of much help
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| doc179
Forum Guru
Topics: 67
Posts: 1,217
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This is what I think: considering class switching , the gene for the constant regions of the heavy chain should be on a single chromosome and so I think the answer is A. Let me know the correct answer. Thanks
GL
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| smal
Forum Guru
Topics: 140
Posts: 727
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A.
genes for heavy chain on 1 chromosome(ch 14) and genes for light on another.am making up this explaination am not sure abt it.
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| Palaniappan
Forum Senior
Topics: 30
Posts: 148
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yes.tha answer is a But..could you please explain more about the gamma,alpha,kappa chain.Which are the genes for the constant region??
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| blueocean
Forum Senior
Topics: 15
Posts: 195
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Basically are 5 genes for C domain- H chain- (alpha, epsilon, delta, gama, mu) on the 14th chromosome. For L chain the genes are on the cz 2 (kappa) and 22 ( lambda).
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| Palaniappan
Forum Senior
Topics: 30
Posts: 148
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Thanks a lot blueocean!!!
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