drugAddict wrote:
Pyrazinamide, hydralazine and Isoniazid all have WHAT in common?
If you had put ,
- procainamide
- INH
- Hydralazine
together ,then I would have said
All of these are
- Notorius for causing drug induced lupus
- metabolized by "acetylation"
Best of luck
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| muzammil
Forum Guru
Topics: 16
Posts: 664
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alll are metabolized by N-actyl transfarase and all cause SLE in slow acetylators. in order of procainamide>hydralazine>isoniazid
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| drugAddict
Forum Newbie
Topics: 3
Posts: 12
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leopard,muzammil: you are right IF the question had procainamide.
pyrazinamide,hydralazine, isoniazid
- all are implicated in SLE
- all cause hepatotoxicity
FYI, all are hydrazine drug derivatves
Good luck to all
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