oncogenes

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oncogenes

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docarchana
Forum Guru

Topics: 70
Posts: 515

09/26/06 - 10:03 AM

Some oncogenes are mutants of normal cell surface receptors that have tyrosine protein kinase motifs in their cytoplasmic domains.
The type of mutation of such a receptor that is most likely to result in cell transformation is a mutant protein with which of the following characteristics ?

a.-constitutive activation of cellualar transcription
b.-deletion of the cytoplasmic domain
c.-failure to become phosphorylated upon receving the signal
d.-failure to receive the signal that normally activates cellualr trascription
e.-recognition of a different signal than usual

docarchana
Forum Guru

Topics: 70
Posts: 515

09/26/06 - 10:04 AM

its nbme 4. sorry dint label

yasmeen
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09/26/06 - 11:37 AM

blueocean
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Topics: 15
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09/26/06 - 12:26 PM

C
http://arnica.csustan.edu/grobner/biol3310/kinase...

eytanraz
Forum Newbie

Topics: 1
Posts: 68

09/30/06 - 10:06 AM

i GO WITH a, SINCE THE TRANSFOMRATION IS CAUSED BY THE ACTIVATION OF THE TYROSINE KINASE. iF IT IS NOT PHOSPHORYLATED, IT IS INACTIVE!

DanVitor
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Posts: 34

09/30/06 - 12:04 PM

Agree with eyatanraz

muzammil
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09/30/06 - 12:54 PM

well i wud go for c

fongch
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Topics: 71
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10/01/06 - 08:45 PM

The answer obviously is A.

MD_toronto
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10/12/06 - 09:32 AM

proctalgia
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Topics: 2
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10/14/06 - 06:17 PM

#10

i go for C, ?? pls explain y A is correct

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