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Kaplan Qbank USMLE



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A bacterium harboring a 15,000 base pair (bp) plasmid that encodes resistance to tetracycline and ampicillin segregates mutants that lose resistance to either drug. Each independent mutant plasmid appears to increase in size by approx. 5200 bp. Which molecular event best explains these findings?
a. formation of plasmid concatemers
b. formation of pyrimidine dimmers
c. homologous recombination
d. insertion of a transposon
e. slip-stranded DNA replication errors









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