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Kaplan Qbank USMLE



Author10 Posts
  #1

An asymptomatic 42-year-old man with essential hypertension is started on an angiotensin-converting enzyme inhibitor. Which of the following shows the most likely effect of treatment on circulating levels of aldosterone, renin, and bradykinin?


Aldosterone/Renin/Bradykinin

A) ↓ ↓ ↓

B) ↓ ↓ ↑

C) ↓ ↑ ↑

D) ↑ ↑ no change

E) ↑ ↑ ↑

F) ↑ ↑ ↓



  #2

C

  #3

Yes. C

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  #4

C

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  #5

ACEI block synthesis of AII and Aldo
AI and renin increase because they are both before the block
BK increases (cuz ACE is involved also in the kinines system) and causes cough and angioedema, the main side-effects of ACEIs

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Traveler, there are no roads. Roads are made by walking.

  #6

ANSWER IS B
bc ACEI Blocks Conversion of Angiotensin 1 to angiotensin II so increase angiotensin I decreases renin via negative feedback . dec angiotensin II decreases aldosterone and increases bradykynin which causes cough

  #7

B or C I think C

What is the stimuluis for Renin? FA says , with ACE inhibitors the renin release is increased due to loss of negetive feedback inhibition.
I guess here the stimulus is Low BP.

  #8

C

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  #9

man...this q is so classic...

no doubt C

cant wait to see this q on my board...

  #10

itz C for sure.........

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