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Kaplan Qbank USMLE



Author5 Posts
  #1

A 45-year-old comatose man is brought to the emergency department. Physical examination reveals profound dehydration and tachycardia. Laboratory studies show severe hyperglycemia (800 mg/dL) and glycosuria. Plasma osmolality is 340 mosm/L and there is no significant ketosis. It was determined that he was taking an arterial vasodilator that has which of the following mechanisms?
A. Activates K+ATP channels
B. Activates nitric oxide synthase
C. Activates voltage-gated Ca2+ channels
D. Blocks alpha-1 adrenergic receptors
E. Blocks angiotensin II receptors
F. Blocks beta-1 adrenergic receptors


  #2

The anwer is "A"

Diazoxide activates the ATP dependent K channels in the blood vessels and Beta cells of the pancreas.Other indication of diazoxide is "Insulinoma"


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  #3

A. Diazoxide

also used in insulinoma


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  #4

correct a...

  #5

it has just the opposite action of sulfonylureas







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