rei
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To my understanding,
sepsis = systemic inflammatory response syndrome (SIRS) + documented source of infection
bacteremia also present in sepsis
septicemia = bacteremia + toxemia + SIRS + usu. caused by Gram -ve bacteria
so what is the difference between the two?
thank you.
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| hitesh
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Usually, these terms are used interchangeably. but technically speaking, septicemia is same as bacteremia, while sepsis is the systemic inflammatory response to it.
septicemia is usually associated with sepsis. However, this response can sometimes be significantly diminished, eg. in children with inherited disorders of nuclear factor (NF)-KB-mediated immunity.
also see http://www.ccmtutorials.com/infection/sepsis/page...
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| rei
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thx
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| tolito
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i think taht septisemia implies multiplication of the bacteria in the blood stream while bacteraemia means presence of bacteria in teh blood stream. these are two different entities, cos the response to septiceamia is more violent than for bacteremia. B. mia may be controlled by the body while septicemia has overwhelmed the bodies immunoty. please correct me if i am wrong.
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| robin082006
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yeah, agree with tolito.
Septicemia is more severe than bacteremia.
Bacteremia may be present without any clinical disturbances.
Septicemia= bacteremia+ disturbances (fever, increased WBCs, hemodynamic disorders, and ect)..
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| hitesh
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well, i'm sorry. i guess you guys are right. so,are we saying that septicemia is sepsis in response to bactremia, while sepsis is a broader term ( SIRS + a documented source of infection), ie. sepsis may not necessarily have bacteremia?
PS: i just realised that there has already been a discussion on this issue in another forum on prep4usmle.com. kindly read this too http://www.prep4usmle.com/forum/thread/9734
Edited by hitesh on 10/10/06 - 04:14 PM
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