drpkaur
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A 15-year-old boy presents to the emergency department in critical condition with Aspergillus nidulans pneumonia. His past history includes recurrent infections since infancy. Organisms found in previous infections included Pseudomonas aeruginosa and Serratia marcescens. Which of the following enzymes normally produces a cofactor necessary for killing these organisms?
A. Glucose-6-phosphate dehydrogenase
B. Glutathione peroxidase
C. Glutathione reductase
D. Pyruvate dehydrogenase
E. Pyruvate kinase
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| suv
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A
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| Ivil
Forum Senior
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A. G6PD produces NADPH via HMP shunt
NADPH is the cofactor for NADPH Oxidase
so this results in a scenario similar to chronic granulomatous disease
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