drpkaur Forum Guru

Topics: 196 Posts: 810
| | 09/14/06 - 09:55 AM  
 
   
 
|   #1 |
A 45-year-old patient reports to his primary care physician complaining of chronic, burning epigastric pain. A diagnosis of gastroesophageal reflux disease is made. In addition to this condition, this patient is anticoagulated with warfarin for atrial fibrillation. Which of the following medications would be contraindicated in this patient? A. Aluminum hydroxide B. Cimetidine C. Misoprostol D. Omeprazole E. Sucralfate
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| suv Forum Elite
Topics: 43 Posts: 233
| | 09/14/06 - 10:03 AM  
 
   
 
|   #2 |
cimetidine increase the actions of warfarin so that drug would be contraindicated
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| drfax Forum Elite

Topics: 21 Posts: 243
| | 09/14/06 - 01:41 PM  
 
   
 
|   #3 |
Cimetidine
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| Leopard Forum Guru

Topics: 30 Posts: 401
| | 09/14/06 - 04:01 PM  
 
   
 
|   #4 |
Sorry to say both Cimetidine and Omeprarzole increase the action of Warfarin and bleeding tendency. I do not know which choice to select.
Attached Files:
Warfarin interaction.pdf (128 KB, 12 downloads)
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| suv Forum Elite
Topics: 43 Posts: 233
| | 09/14/06 - 04:33 PM  
 
   
 
|   #5 |
thanks for the list leopard since cimetidine is a major p 450 inhibitor that would be a better choice among the two feel free to correct me!
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| docarchana Forum Guru
Topics: 70 Posts: 515
| | 09/14/06 - 04:42 PM  
 
   
 
|   #6 |
can someone plz post whats the drug interaction of warfarin with 1)phenytoin, 2)carbamazepine?
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| suv Forum Elite
Topics: 43 Posts: 233
| | 09/14/06 - 04:45 PM  
 
   
 
|   #7 |
hey archana see the file attached by leopard hope it helps
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| docarchana Forum Guru
Topics: 70 Posts: 515
| | 09/14/06 - 04:50 PM  
 
   
 
|   #8 |
thanku suv. acc to the link, CBZ- action of warfarin decrease phenytoin - variable. both phenytoin & CBZ are inducers of CYP. so why the diff?
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| drpkaur Forum Guru

Topics: 196 Posts: 810
| | 09/14/06 - 09:27 PM  
 
   
 
|   #9 |
suv you are correct..cimetidine is the best and correct answer.
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| docswapna Forum Senior
Topics: 61 Posts: 229
| | 09/14/06 - 10:15 PM  
 
   
 
|   #10 |
what is the normal INR value?
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