MRMAVERICK
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A 57 year-old man presents to the Emergency Department w/ a nosebleed for the past 2 hours. The patient received a prosthetic heart valve 5 months ago and is currently taking warfarin (7.5 mg per day) and oral antibiotics. Laboratory evaluation reveals an IRN of 6.4. Which of the following antibiotics is the patient most likely taking?
A. Ampicillin
B. Cephalexin
C. Nitrofurantoin
D. Norfloxacin
E. Phenazopyridine
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| vanshita
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| drpkaur
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| docarchana
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fluroquinolones inhibit CYP1A. warfarin is metabolised by CYP3A4. how can we ans this q as norfloxacin. just a doubt. actually im not good in this topic. someone plz help.
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| new_n_lost
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Warfarin is metabolized by CypIA2 n fluoroquinolones do inhibit it
Katzung Board Review 7th ed. pg. 34 table 4-4
here is a link too
http://www.hemosense.com/docs/5500331_TechBull110...'warfarin%20drug%20interactions'
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| drfax
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