Leopard
Forum Guru
Topics: 30
Posts: 401
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NAD and NADPH ,both are Niacin derivatives .What is the difference in their action and Function?
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| docarchana
Forum Guru
Topics: 70
Posts: 515
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NAD - role in ATP production (ETC)
NADPH - role in HMP shunt.
i think u want some thing more. 
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| docarchana
Forum Guru
Topics: 70
Posts: 515
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NADPH - fatty acid synthesis
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| eytanraz
Forum Newbie
Topics: 1
Posts: 68
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u have to compare nad+ with nadp+ and nadh with nadph: from lippincott:
"nadp+ differs from nad+ only by the prese3nce of a phosphate group on one of the ribose units. This seemingly small change allows nadp+ to interact with specific enzymes. In the steady state the ratio nadp+/nadph in the cytosol of hepatocytes is 0.1 which favors the use of nadph in reductive byosinthetic reactions. This contrasts with the high ratio nad+/nadh, that is 1000 in the cytosol of hepatocytes which favors an oxidative role for nad+"
USES OF NADP+/NADPH:
-reductive byointhesis
-reductionm of hydrogen peroxide: glutathione reductase use nadph as reductive agent (remember g6pd deficiency!)
-cytochrome p450 monoxygenase system
-phagocytosis by white cells
-synthesis of nitric oxide (substrate of nitric oxid synthase are arginine, oxygen and nadph)
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| docarchana
Forum Guru
Topics: 70
Posts: 515
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whats ur say leopard??
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