drpkaur
Forum Guru
Topics: 196
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A patient with a deficiency in the enzyme, thioesterase, is unable to release a fully formed fatty acid from fatty acid synthase. The name for that fatty acid is
A. Hexadecanoic acid
B. cis-D9-Octadecanoic acid
C. Octadecanoic acid
D. cis-D9,D12-Octadecanoic acid
E. cis-D9-Hexadecanoic acid
D=delta
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| Leopard
Forum Guru
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oooooooooooooooooooops
Help ,help ,help
My Brain has been damaged because of this question .
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| blueocean
Forum Senior
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maybe it's A- thioesterase catalyses the last step in synthesis of FA .Anyway, it can be just a saturated FA which means A/C.
What a question! Where you have from?
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| blueocean
Forum Senior
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drpkaur, what is the answer?
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| drpkaur
Forum Guru
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Posts: 810
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it's A...
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| blueocean
Forum Senior
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thank you!
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| docarchana
Forum Guru
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I think A means palmitic acid - right?? (16carbon)
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| drpkaur
Forum Guru
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Posts: 810
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yeah............
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| eytanraz
Forum Newbie
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Posts: 68
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thioesterase, aka called palmitoyl thioesterase, is the last enzyme of the fatty acid synthase complex. During the formation of the fatty acid, the growing molecule is keep attached to the enzyme by the use of a thioestere link between the carbon number 1 of the fatty acid and the atom of sulfur of a molecule of phosphopantheine that is attached to the enzyme.
so....when the synthesis is finished and the growing molecule had reached the shape of a 16 carbon saturated fatty acid, there's the need to solve that thioestere link to give palmitic acid....by means of thioesterase
hexa means six, decanoic means ten, and 6+10 is 16, and palmitic acid we have to remember that has 16 carbon units.
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